Some hereditary abnormalities, excessive use of alcohol and medication, cancer or viruses leading to hepatitis may induce irreversible damages in the liver. In this case, liver shrinks and hardens, and lumps with varying size develop, resulting in occurrence of cirrhosis. Cirrhosis can cause fatal results, including but not limited to bleeding, jaundice, ascites, infections and accumulation of toxic wastes in the body as well as coma. In the end, the only choice is liver transplant.

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